So I got Elite Dangerous recently and at first i was considering buying a HOTUS setup, but it turned out i actually really like the flight controls with a mouse and keyboard. Luckily someone told me to try switching Yaw to the X axis on my mouse, Roll to the A and D keys and throttle to the mouse wheel and that helped a lot.
I never played EVE, so i'm not sure how the controls work differently, but the flight controls in Elite Dangerous seem great to me so i hope we end up with something similar in DU.
I realized that i have more then 30 years of experience with a mouse and keyboard and none at all flying an actual jet or using a HOTUS so i should probably just stick with the mouse and keyboard.
Learning to orient yourself in 3d space is rough, i was spinning around drunkenly and crashing into stuff for hours in the tutorial before i got the hang of it.